PPARβ interprets a chromatin signature of pluripotency to promote embryonic differentiation at gastrulation

• المؤلفون الرئيسيون: Rotman, Nicolas, Guex, Nicolas, Gouranton, Erwan, Wahli, Walter
• مؤلفون آخرون: Knott, Jason Glenn
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Medicine
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/102143; http://hdl.handle.net/10220/18832

Epigenetic post-transcriptional modifications of histone tails are thought to help in coordinating gene expression during development. An epigenetic signature is set in pluripotent cells and interpreted later at the onset of differentiation. In pluripotent cells, epigenetic marks normally associated...