Co-motif discovery identifies an Esrrb-Sox2-DNA ternary complex as a mediator of transcriptional differences between mouse embryonic and epiblast stem cells

Transcription factors (TF) often bind in heterodimeric complexes with each TF recognizing a specific neighboring cis element in the regulatory region of the genome. Comprehension of this DNA motif grammar is opaque, yet recent developments have allowed the interrogation of genome-wide TF binding sit...

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Bibliographic Details
Main Authors: Mistri, Tapan Kumar, Rahmani, Mehran, Woon, Chow Thai, Ng, Calista Keow Leng, Jauch, Ralf, Robson, Paul, Hutchins, Andrew Paul, Choo, Siew Hua
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/102237
http://hdl.handle.net/10220/18922
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Institution: Nanyang Technological University
Language: English