Importance of extended protease substrate recognition motifs in steering BNIP-2 cleavage by human and mouse granzymes B

Background Previous screening of the substrate repertoires and substrate specificity profiles of granzymes resulted in long substrate lists highly likely containing bystander substrates. Here, a recently developed degradomics technology that allows distinguishing efficiently from less efficiently cl...

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Main Authors: Van Damme, Petra, Plasman, Kim, Vandemoortele, Giel, Jonckheere, Veronique, Maurer-Stroh, Sebastian, Gevaert, Kris
其他作者: School of Biological Sciences
格式: Article
語言:English
出版: 2014
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在線閱讀:https://hdl.handle.net/10356/102506
http://hdl.handle.net/10220/24274
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機構: Nanyang Technological University
語言: English