Immunomodulatory effects of pneumococcal extracellular vesicles on cellular and humoral host defenses

• Main Authors: Codemo, Mario, Muschiol, Sandra, Iovino, Federico, Nannapaneni, Priyanka, Plant, Laura, Wai, Sun Nyunt, Henriques-Normark, Birgitta
• Other Authors: Rappuoli, Rino
• Format: Article
• Language: English
• Published: 2019
• Subjects: Cellular and Humoral Defense; Streptococcus Pneumoniae
• Online Access: https://hdl.handle.net/10356/102673; http://hdl.handle.net/10220/50282
• Institution: Nanyang Technological University

Gram-positive bacteria, including the major respiratory pathogen Streptococcus pneumoniae, were recently shown to produce extracellular vesicles (EVs) that likely originate from the plasma membrane and are released into the extracellular environment. EVs may function as cargo for many bacterial prot...