Modulating human mesenchymal stem cell plasticity using micropatterning technique

• Main Authors: Tijore, Ajay, Wen, Feng, Lam, Chee Ren Ivan, Tay, Chor Yong, Tan, Lay Poh
• Other Authors: Papaccio, Gianpaolo
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/103000; http://hdl.handle.net/10220/24387
• Institution: Nanyang Technological University

In our previous work, we have reported that enforced elongation of human mesenchymal stem cells (hMSCs) through micropatterning promoted their myocardial lineage commitment. However, whether this approach is robust enough to retain the commitment when subsequently subjected to different conditions r...