One-pot synthesis of β-N-glycosyl imidazole analogues via a palladium-catalysed decarboxylative allylation

• Main Authors: Xiang, Shaohua, He, Jingxi, Ma, Jimei, Liu, Xue-Wei
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
• Online Access: https://hdl.handle.net/10356/103109; http://hdl.handle.net/10220/24357
• Institution: Nanyang Technological University

A concise and highly efficient strategy for the synthesis of N-glycosyl imidazole analogues is reported. This reaction is based on a palladium catalysed decarboxylative allylation and three steps, namely, carbamation, decarboxylation and allylation are involved. All the substrates can afford the des...