The metal ion-dependent adhesion site motif of the Enterococcus faecalis EbpA pilin mediates pilus function in catheter-associated urinary tract infection

• المؤلفون الرئيسيون: Nielsen, Hailyn V., Guiton, Pascale S., Kline, Kimberly A., Port, Gary C., Pinkner, Jerome S., Neiers, Fabrice, Normark, Staffan, Henriques-Normark, Birgitta, Caparon, Michael G., Hultgren, Scott J.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/103127; http://hdl.handle.net/10220/19132
• المؤسسة: Nanyang Technological University

Though the bacterial opportunist Enterococcus faecalis causes a myriad of hospital-acquired infections (HAIs), including catheter-associated urinary tract infections (CAUTIs), little is known about the virulence mechanisms that it employs. However, the endocarditis- and biofilm-associated pilus (Ebp...