Amplified detection of femtomolar DNA based on a one-to-few recognition reaction between DNA-Au conjugate and target DNA

A sensitive electrochemical DNA biosensor based on the amplification of Au nanoparticles (AuNPs) has been developed. The AuNPs were modified with two types of signaling reporter DNAs, i.e. a methylene blue probe (MB-probe 2-SH) and T10 with a methylene blue signaling molecule (MB-T10-SH), forming DN...

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Bibliographic Details
Main Authors: Wang, Zhijuan, Zhang, Juan, Zhu, Changfeng, Wu, Shixin, Mandler, Daniel, Marks, Robert S., Zhang, Hua
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/103160
http://hdl.handle.net/10220/24464
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Institution: Nanyang Technological University
Language: English