Amplified detection of femtomolar DNA based on a one-to-few recognition reaction between DNA-Au conjugate and target DNA
A sensitive electrochemical DNA biosensor based on the amplification of Au nanoparticles (AuNPs) has been developed. The AuNPs were modified with two types of signaling reporter DNAs, i.e. a methylene blue probe (MB-probe 2-SH) and T10 with a methylene blue signaling molecule (MB-T10-SH), forming DN...
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Main Authors: | Wang, Zhijuan, Zhang, Juan, Zhu, Changfeng, Wu, Shixin, Mandler, Daniel, Marks, Robert S., Zhang, Hua |
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Other Authors: | School of Materials Science & Engineering |
Format: | Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/103160 http://hdl.handle.net/10220/24464 |
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Institution: | Nanyang Technological University |
Language: | English |
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