Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging

Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging

We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the r...

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Bibliographic Details
Main Authors: Kong, Kien Voon, Liao, Lun-De, Lam, Zhiyong, Thakor, Nitish V., Leong, Weng Kee, Olivo, Malini
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2014
Subjects:
DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
Online Access:https://hdl.handle.net/10356/103226
http://hdl.handle.net/10220/24381
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Institution: Nanyang Technological University
Language: English
Description
Summary:We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the rat cerebral cortex vasculature was observed using in vivo dark-field photoacoustic microscopy.

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