Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging

We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the r...

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Main Authors: Kong, Kien Voon, Liao, Lun-De, Lam, Zhiyong, Thakor, Nitish V., Leong, Weng Kee, Olivo, Malini
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2014
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Online Access:https://hdl.handle.net/10356/103226
http://hdl.handle.net/10220/24381
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1032262023-02-28T19:43:37Z Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging Kong, Kien Voon Liao, Lun-De Lam, Zhiyong Thakor, Nitish V. Leong, Weng Kee Olivo, Malini School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the rat cerebral cortex vasculature was observed using in vivo dark-field photoacoustic microscopy. ASTAR (Agency for Sci., Tech. and Research, S’pore) Accepted version 2014-12-09T06:02:51Z 2019-12-06T21:07:53Z 2014-12-09T06:02:51Z 2019-12-06T21:07:53Z 2014 2014 Journal Article Kong, K. V., Liao, L.-D., Lam, Z., Thakor, N. V., Leong, W. K., & Olivo, M. (2014). Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging. Chemical communications, 50(20), 2601-2603. https://hdl.handle.net/10356/103226 http://hdl.handle.net/10220/24381 10.1039/c3cc48529c en Chemical communications © 2014 Royal Society of Chemistry. This is the author created version of a work that has been peer reviewed and accepted for publication by Chemical Communications, Royal Society of Chemistry. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [Article DOI: http://dx.doi.org/10.1039/c3cc48529c]. 3 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
spellingShingle DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
Kong, Kien Voon
Liao, Lun-De
Lam, Zhiyong
Thakor, Nitish V.
Leong, Weng Kee
Olivo, Malini
Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging
description We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the rat cerebral cortex vasculature was observed using in vivo dark-field photoacoustic microscopy.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Kong, Kien Voon
Liao, Lun-De
Lam, Zhiyong
Thakor, Nitish V.
Leong, Weng Kee
Olivo, Malini
format Article
author Kong, Kien Voon
Liao, Lun-De
Lam, Zhiyong
Thakor, Nitish V.
Leong, Weng Kee
Olivo, Malini
author_sort Kong, Kien Voon
title Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging
title_short Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging
title_full Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging
title_fullStr Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging
title_full_unstemmed Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging
title_sort organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging
publishDate 2014
url https://hdl.handle.net/10356/103226
http://hdl.handle.net/10220/24381
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