Viroporin activity of the foot-and-mouth disease virus non-structural 2B protein

• Main Authors: Ao, Da, Guo, Hui-Chen, Sun, Shi-Qi, Sun, De-Hui, Fung, To Sing, Wei, Yan-Quan, Han, Shi-Chong, Yao, Xue-Ping, Cao, Sui-Zhong, Liu, Ding Xiang, Liu, Xiang-Tao
• Other Authors: Liang, Chen
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/103364; http://hdl.handle.net/10220/25827
• Institution: Nanyang Technological University

Viroporins are a family of low-molecular-weight hydrophobic transmembrane proteins that are encoded by various animal viruses. Viroporins form transmembrane pores in host cells via oligomerization, thereby destroying cellular homeostasis and inducing cytopathy for virus replication and virion releas...