Productive entry of foot-and-mouth disease virus via macropinocytosis independent of phosphatidylinositol 3-kinase

Virus entry is an attractive target for therapeutic intervention. Here, using a combination of electron microscopy, immunofluorescence assay, siRNA interference, specific pharmacological inhibitors, and dominant negative mutation, we demonstrated that the entry of foot-and-mouth disease virus (FMDV)...

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Bibliographic Details
Main Authors: Han, Shi-Chong, Guo, Hui-Chen, Sun, Shi-Qi, Jin, Ye, Wei, Yan-Quan, Feng, Xia, Yao, Xue-Ping, Cao, Sui-Zhong, Xiang Liu, Ding, Liu, Xiang-Tao
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87484
http://hdl.handle.net/10220/46731
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Institution: Nanyang Technological University
Language: English