Productive entry of foot-and-mouth disease virus via macropinocytosis independent of phosphatidylinositol 3-kinase
Virus entry is an attractive target for therapeutic intervention. Here, using a combination of electron microscopy, immunofluorescence assay, siRNA interference, specific pharmacological inhibitors, and dominant negative mutation, we demonstrated that the entry of foot-and-mouth disease virus (FMDV)...
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Main Authors: | Han, Shi-Chong, Guo, Hui-Chen, Sun, Shi-Qi, Jin, Ye, Wei, Yan-Quan, Feng, Xia, Yao, Xue-Ping, Cao, Sui-Zhong, Xiang Liu, Ding, Liu, Xiang-Tao |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/87484 http://hdl.handle.net/10220/46731 |
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Institution: | Nanyang Technological University |
Language: | English |
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