Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment

• Main Authors: Cheng, Hong Sheng, Lee, Jeannie Xue Ting, Wahli, Walter, Tan, Nguan Soon
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: DRNTU::Science::Biological sciences; Tumor Microenvironment; Nuclear Receptors
• Online Access: https://hdl.handle.net/10356/103471; http://hdl.handle.net/10220/48069
• Institution: Nanyang Technological University

The tumor microenvironment is a complex and dynamic cellular community comprising the tumor epithelium and various tumor-supporting cells such as immune cells, fibroblasts, immunosuppressive cells, adipose cells, endothelial cells, and pericytes. The interplay between the tumor microenvironment and...