A generic micropatterning platform to direct human mesenchymal stem cells from different origins towards myogenic differentiation

• Main Authors: Tan, Lay Poh, Yu, Ting, Chua, Chee Kai, Tay, Chor Yong, Wen, Feng, Yu, Haiyang, Chan, Jerry Kok Yen, Chong, Mark Seow Khoon, Leong, David Tai Wei
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Chemical engineering::Biochemical engineering
• Online Access: https://hdl.handle.net/10356/103661; http://hdl.handle.net/10220/16726
• Institution: Nanyang Technological University

Human mesenchymal stem cells (MSCs) derived from various origins show varied differentiation capability. Recent work shows that cell shape manipulation via micropatterning can modulate the differentiation of bone-marrow-derived MSCs. Herein, the effect of micropatterning on the myogenesis of MSCs is...