Studying wound repair in the mouse
Animal models of wound healing provide vital insights into the mechanisms and pathophysiology of cutaneous wound repair and are a crucial part of clinical research into the development of new strategies and approaches to rational wound therapy. Although considerable biological variation in the wo...
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| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/103667 http://hdl.handle.net/10220/19287 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Animal models of wound healing provide vital insights into the mechanisms and pathophysiology
of cutaneous wound repair and are a crucial part of clinical research into the
development of new strategies and approaches to rational wound therapy. Although considerable
biological variation in the wound healing response exists even among inbred
animal strains, consistent surgical procedure and wound analysis can yield significant
conclusions. Many different aspects of the healing process can be characterized and
quantified in a reproducible, controlled environment. Here, we detail methods for fullthickness
excisional and incisional wounding and for analysis of wound biopsies. |
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