The potential of the FSP1cre-Pparb/d-/- mouse model for studying juvenile NAFLD

Non-alcoholic fatty liver disease (NAFLD) can progress from steatosis to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation, possibly leading to cirrhosis and hepatocellular carcinoma (HCC). Mice with impaired macrophage activation, when fed a high-fat diet, develop severe NASH...

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Bibliographic Details
Main Authors: Chen, Jiapeng, Zhuang, Yan, Sng, Ming Keat, Tan, Nguan Soon, Wahli, Walter
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142227
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Institution: Nanyang Technological University
Language: English