Modular Synthesis of Multisubstituted Furans through Palladium-Catalyzed Three-Component Condensation of Alkynylbenziodoxoles, Carboxylic Acids, and Imines
Mild and regiocontrolled synthesis of a multisubstituted furan is achieved through Pd(OAc)2-catalyzed room-temperature condensation of an alkynylbenziodoxole, a carboxylic acid, and an enolizable ketimine, which contribute to C1, CO, and C2 fragments, respectively, to the furan skeleton. The reactio...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
2015
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Online Access: | https://hdl.handle.net/10356/103693 http://hdl.handle.net/10220/38788 |
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Institution: | Nanyang Technological University |
Language: | English |