Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds
The first metal-free catalytic hydroboration of carbonyl derivatives has been developed in which a catalytic amount of 1,3,2-diazaphospholene effectively promotes a hydroboration reaction of aliphatic and aromatic aldehydes and ketones. The reaction mechanism involves the cleavage of both the P-O bo...
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sg-ntu-dr.10356-1039392020-03-07T12:34:53Z Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds Chong, Che Chang Hirao, Hajime Kinjo, Rei School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry::Carbanions The first metal-free catalytic hydroboration of carbonyl derivatives has been developed in which a catalytic amount of 1,3,2-diazaphospholene effectively promotes a hydroboration reaction of aliphatic and aromatic aldehydes and ketones. The reaction mechanism involves the cleavage of both the P-O bond of the alkoxyphosphine intermediate and the B-H bond of pinacolborane as well as the formation of P-H and B-O bonds. Thus, the reaction proceeds through a non-metal σ-bond metathesis. Kinetic and computational studies suggest that the σ-bond metathesis occurred in a stepwise but nearly concerted manner. 2015-01-15T04:35:39Z 2019-12-06T21:23:23Z 2015-01-15T04:35:39Z 2019-12-06T21:23:23Z 2015 2015 Journal Article Chong, C. C., Hirao, H., & Kinjo, R. (2015). Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds. Angewandte chemie international edition, 54(1), 190-194. 1433-7851 https://hdl.handle.net/10356/103939 http://hdl.handle.net/10220/24628 10.1002/anie.201408760 en Angewandte chemie international edition © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
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DRNTU::Science::Chemistry::Organic chemistry::Carbanions Chong, Che Chang Hirao, Hajime Kinjo, Rei Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds |
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The first metal-free catalytic hydroboration of carbonyl derivatives has been developed in which a catalytic amount of 1,3,2-diazaphospholene effectively promotes a hydroboration reaction of aliphatic and aromatic aldehydes and ketones. The reaction mechanism involves the cleavage of both the P-O bond of the alkoxyphosphine intermediate and the B-H bond of pinacolborane as well as the formation of P-H and B-O bonds. Thus, the reaction proceeds through a non-metal σ-bond metathesis. Kinetic and computational studies suggest that the σ-bond metathesis occurred in a stepwise but nearly concerted manner. |
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School of Physical and Mathematical Sciences |
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School of Physical and Mathematical Sciences Chong, Che Chang Hirao, Hajime Kinjo, Rei |
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Chong, Che Chang Hirao, Hajime Kinjo, Rei |
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Chong, Che Chang |
title |
Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds |
title_short |
Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds |
title_full |
Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds |
title_fullStr |
Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds |
title_full_unstemmed |
Metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds |
title_sort |
metal-free σ-bond metathesis in 1,3,2-diazaphospholene-catalyzed hydroboration of carbonyl compounds |
publishDate |
2015 |
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https://hdl.handle.net/10356/103939 http://hdl.handle.net/10220/24628 |
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1681048421651185664 |