Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications
A new molecular dyad consisting of a Cy5 chromophore and ferrocene (Fc) and a triad consisting of Cy5, Fc, and β-cyclodextrin (CD) are synthesized and their photophysical properties investigated at both the ensemble and single-molecule levels. Hole transfer efficiency from Cy5 to Fc in the dyad is r...
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sg-ntu-dr.10356-1039532020-03-07T12:34:54Z Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications Wu, Xiangyang Liu, Fang Wells, Kym L. Tan, Serena L. J. Webster, Richard D. Tan, Howe-Siang Zhang, Dawei Xing, Bengang Yeow, Edwin K. L. School of Physical and Mathematical Sciences DRNTU::Science::Chemistry A new molecular dyad consisting of a Cy5 chromophore and ferrocene (Fc) and a triad consisting of Cy5, Fc, and β-cyclodextrin (CD) are synthesized and their photophysical properties investigated at both the ensemble and single-molecule levels. Hole transfer efficiency from Cy5 to Fc in the dyad is reduced upon addition of CD. This is due to an increase in the Cy5-Fc separation (r) when the Fc is encapsulated in the macrocyclic host. On the other hand, the triad adopts either a Fc-CD inclusion complex conformation in which hole transfer quenching of the Cy5 by Fc is minimal or a quasi-static conformation with short r and rapid charge transfer. Single-molecule fluorescence measurements reveal that r is lengthened when the triad molecules are deposited on a glass substrate. By combining intramolecular charge transfer and competitive supramolecular interaction, the triad acts as an efficient chemical sensor to detect different bioactive analytes such as amantadine hydrochloride and sodium lithocholate in aqueous solution and synthetic urine. 2015-01-15T05:04:54Z 2019-12-06T21:23:31Z 2015-01-15T05:04:54Z 2019-12-06T21:23:31Z 2014 2014 Journal Article Wu, X., Liu, F., Wells, K. L., Tan, S. L. J., Webster, R. D., Tan, H.-S., et al. (2014). Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications. Chemistry - a European journal, 21(8), 3387–3398. 0947-6539 https://hdl.handle.net/10356/103953 http://hdl.handle.net/10220/24631 10.1002/chem.201404360 en Chemistry - a European journal © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
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DRNTU::Science::Chemistry Wu, Xiangyang Liu, Fang Wells, Kym L. Tan, Serena L. J. Webster, Richard D. Tan, Howe-Siang Zhang, Dawei Xing, Bengang Yeow, Edwin K. L. Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications |
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A new molecular dyad consisting of a Cy5 chromophore and ferrocene (Fc) and a triad consisting of Cy5, Fc, and β-cyclodextrin (CD) are synthesized and their photophysical properties investigated at both the ensemble and single-molecule levels. Hole transfer efficiency from Cy5 to Fc in the dyad is reduced upon addition of CD. This is due to an increase in the Cy5-Fc separation (r) when the Fc is encapsulated in the macrocyclic host. On the other hand, the triad adopts either a Fc-CD inclusion complex conformation in which hole transfer quenching of the Cy5 by Fc is minimal or a quasi-static conformation with short r and rapid charge transfer. Single-molecule fluorescence measurements reveal that r is lengthened when the triad molecules are deposited on a glass substrate. By combining intramolecular charge transfer and competitive supramolecular interaction, the triad acts as an efficient chemical sensor to detect different bioactive analytes such as amantadine hydrochloride and sodium lithocholate in aqueous solution and synthetic urine. |
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School of Physical and Mathematical Sciences |
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School of Physical and Mathematical Sciences Wu, Xiangyang Liu, Fang Wells, Kym L. Tan, Serena L. J. Webster, Richard D. Tan, Howe-Siang Zhang, Dawei Xing, Bengang Yeow, Edwin K. L. |
format |
Article |
author |
Wu, Xiangyang Liu, Fang Wells, Kym L. Tan, Serena L. J. Webster, Richard D. Tan, Howe-Siang Zhang, Dawei Xing, Bengang Yeow, Edwin K. L. |
author_sort |
Wu, Xiangyang |
title |
Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications |
title_short |
Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications |
title_full |
Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications |
title_fullStr |
Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications |
title_full_unstemmed |
Interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications |
title_sort |
interplay of hole transfer and host-guest interaction in molecular dyad and triad : ensemble and single-molecule spectroscopy and sensing applications |
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2015 |
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https://hdl.handle.net/10356/103953 http://hdl.handle.net/10220/24631 |
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1681041815960027136 |