Ursolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells

• Main Authors: Kim, Seong-Hoon, Ryu, Hye Guk, Lee, Juhyun, Shin, Joon, Harikishore, Amaravadhi, Jung, Hoe-Youn, Kim, Ye Seul, Lyu, Ha-Na, Oh, Eunji, Baek, Nam-In, Choi, Kwan-Yong, Yoon, Ho Sup, Kim, Kyong-Tai
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2015
• Online Access: https://hdl.handle.net/10356/103986; http://hdl.handle.net/10220/38799
• Institution: Nanyang Technological University

Many mitotic kinases have been targeted for the development of anti-cancer drugs, and inhibitors of these kinases have been expected to perform well for cancer therapy. Efforts focused on selecting good targets and finding specific drugs to target are especially needed, largely due to the increased...