Photocontrolled nuclear-targeted drug delivery by single component photoresponsive fluorescent organic nanoparticles of acridin-9-methanol

• Main Authors: Banerjee, Deb Ranjan, Ghosh, Sudip Kumar, Nguyen, Kim Truc, Ma, Xing, Qu, Qiuyu, Zhao, Yanli, Pradeep Singh, N. D., Jana, Avijit, Saha, Biswajit
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Chemistry::Organic chemistry
• Online Access: https://hdl.handle.net/10356/104152; http://hdl.handle.net/10220/19434
• Institution: Nanyang Technological University

We report for the first time an organic nanoparticle based nuclear-targeted photoresponsive drug delivery system (DDS) for regulated anticancer drug release. Acridin-9-methanol fluorescent organic nanoparticles used in this DDS performed three important roles: (i) ″nuclear-targeted nanocarrier″ for...