Chitosan microsphere scaffold tethered with RGD-conjugated poly(methacrylic acid) brushes as effective carriers for the endothelial cells

• Main Authors: Pehkonen, Simo O., Yang, Zhenyi, Yuan, Shaojun, Liang, Bin, Liu, Yang, Choong, Cleo Swee Neo
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine::Tissue engineering
• Online Access: https://hdl.handle.net/10356/104158; http://hdl.handle.net/10220/19856
• Institution: Nanyang Technological University

Endothelial cell–matrix interactions play a vital role in promoting vascularization of engineered tissues. The current study reports a facile and controllable method to develop a RGD peptide-functionalized chitosan microsphere scaffolds for rapid cell expansion of human umbilical vein endothelial ce...