Engineering the Saccharomyces cerevisiae β-oxidation pathway to increase medium chain fatty acid production as potential biofuel

• Main Authors: Chen, Liwei, Zhang, Jianhua, Chen, Wei Ning
• Other Authors: Elias, Dwayne
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Chemical engineering::Biochemical engineering; DRNTU::Engineering::Chemical engineering::Fuel
• Online Access: https://hdl.handle.net/10356/104178; http://hdl.handle.net/10220/19518
• Institution: Nanyang Technological University

Fatty acid-derived biofuels and biochemicals can be produced in microbes using β-oxidation pathway engineering. In this study, the β-oxidation pathway of Saccharomyces cerevisiae was engineered to accumulate a higher ratio of medium chain fatty acids (MCFAs) when cells were grown on fatty acid-rich...