Identification of cis-acting elements and splicing factors involved in the regulation of BIM pre-mRNA splicing
Aberrant changes in the expression of the pro-apoptotic protein, BCL-2-like 11 (BIM), can result in either impaired or excessive apoptosis, which can contribute to tumorigenesis and degenerative disorders, respectively. Altering BIM pre-mRNA splicing is an attractive approach to modulate apoptosis b...
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/104198 http://hdl.handle.net/10220/19565 |
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| Institution: | Nanyang Technological University |
| Language: | English |