DNA-templated silver nanoclusters for multiplexed fluorescent DNA detection

Novel label-free/conjugation-free molecular beacons are designed based on DNA templated-silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in-situ and real-time analysis. This study demonstrates a new method for multiplexd detection o...

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Bibliographic Details
Main Authors: Zhu, Changfeng, Zhang, Lei, Tan, Chaoliang, Yang, Jian, Chen, Bo, Wang, Lianhui, Zhang, Hua, Zhang, Ying
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/104208
http://hdl.handle.net/10220/24683
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Institution: Nanyang Technological University
Language: English
Description
Summary:Novel label-free/conjugation-free molecular beacons are designed based on DNA templated-silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in-situ and real-time analysis. This study demonstrates a new method for multiplexd detection of biological molecules by using fluorescent Ag nanocluster-based molecular beacon probes.