N-heterocyclic carbene-catalyzed [3+4] cycloaddition and kinetic resolution of azomethine imines

• المؤلفون الرئيسيون: Wang, Ming, Huang, Zhijian, Xu, Jianfeng, Chi, Robin Yonggui
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Chemistry::Organic chemistry
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/104218; http://hdl.handle.net/10220/19444
• المؤسسة: Nanyang Technological University

The first N-heterocyclic carbene (NHC)-catalyzed [3+4] cycloaddition of azomethine imines and enals is disclosed. Oxidative catalytic remote activation of enals affords 1,4-dipolarophile intermediates that react with 1,3-dipolar azomethine imines to generate dinitrogen-fused seven-membered heterocyc...