Kindlin-3 mediates integrin αLβ2 outside-in signaling, and it interacts with scaffold protein receptor for activated-c kinase 1 (RACK1)

• المؤلفون الرئيسيون: Cornvik, Tobias Carl, Ruedl, Christiane, Feng, Chen, Li, Yan Feng, Yau, Yin Hoe, Lee, Hui-Shan, Tang, Xiao-Yan, Xue, Zhi-Hong, Zhou, Yi-Chao, Lim, Wei-Min, Shochat, Susana Geifman, Tan, Suet Mien
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/104232; http://hdl.handle.net/10220/16987
• المؤسسة: Nanyang Technological University

Integrins are heterodimeric type I membrane cell adhesion molecules that are involved in many biological processes. Integrins are bidirectional signal transducers because their cytoplasmic tails are docking sites for cytoskeletal and signaling molecules. Kindlins are cytoplasmic molecules that media...