α-palladation of Imines as entry to dehydrogenative heck reaction: Aerobic oxidative cyclization of N-Allylimines to Pyrroles

• Main Authors: Ding, Zhenhua, Gao, Ke, Chen, Zhiyuan, Lu, Beili, Yoshikai, Naohiko
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Chemistry
• Online Access: https://hdl.handle.net/10356/104402; http://hdl.handle.net/10220/16559
• Institution: Nanyang Technological University

We report here a palladium(II)-catalyzed oxidative cyclization reaction of N-allylimines derived from methyl ketones, typically acetophenones, affording pyrrole derivatives at room temperature under oxygen atmosphere. The reaction likely proceeds through α-palladation of the imine followed by olefin...