Genetic polymorphism and natural selection in the C-terminal 42 kDa region of merozoite surface protein-1 (MSP-1) among Plasmodium knowlesi samples from Malaysia

Genetic polymorphism and natural selection in the C-terminal 42 kDa region of merozoite surface protein-1 (MSP-1) among Plasmodium knowlesi samples from Malaysia

Background: The merozoite surface protein-1 (MSP-1) gene encodes for a leading malaria vaccine candidate antigen. However, its extensive polymorphic nature represents a major obstacle to the development of a protective vaccine. Previously, a pilot study was carried out to explore the sequence variat...

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Bibliographic Details
Main Authors: Rajoo, Yamuna, Choy, Seow Huey, Yap, Nan Jiun, Vythilingam, Indra, Hoh, Boon Peng, Goh, Xiang Ting, Muslim, Azdayanti, Ngui, Romano, William, Timothy, Yeo, Tsin Wen, Lim, Yvonne Ai-Lian
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2019
Subjects:
Malaysia
DRNTU::Science::Medicine
Merozoite Surface Protein
Online Access:https://hdl.handle.net/10356/104403
http://hdl.handle.net/10220/47396
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/104403
http://hdl.handle.net/10220/47396

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