Genetic polymorphism and natural selection in the C-terminal 42 kDa region of merozoite surface protein-1 (MSP-1) among Plasmodium knowlesi samples from Malaysia
Background: The merozoite surface protein-1 (MSP-1) gene encodes for a leading malaria vaccine candidate antigen. However, its extensive polymorphic nature represents a major obstacle to the development of a protective vaccine. Previously, a pilot study was carried out to explore the sequence variat...
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Main Authors: | Rajoo, Yamuna, Choy, Seow Huey, Yap, Nan Jiun, Vythilingam, Indra, Hoh, Boon Peng, Goh, Xiang Ting, Muslim, Azdayanti, Ngui, Romano, William, Timothy, Yeo, Tsin Wen, Lim, Yvonne Ai-Lian |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/104403 http://hdl.handle.net/10220/47396 |
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Institution: | Nanyang Technological University |
Language: | English |
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