The role of microglia in bacterial meningitis : inflammatory response, experimental models and new neuroprotective therapeutic strategies

• Main Authors: Thorsdottir, Sigrun, Henriques-Normark, Birgitta, Iovino, Federico
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2019
• Subjects: Bacterial Meningitis; DRNTU::Science::Biological sciences; Microglia
• Online Access: https://hdl.handle.net/10356/104788; http://hdl.handle.net/10220/48640
• Institution: Nanyang Technological University

Microglia have a pivotal role in the pathophysiology of bacterial meningitis. The goal of this review is to provide an overview on how microglia respond to bacterial pathogens targeting the brain, how the interplay between microglia and bacteria can be studied experimentally, and possible ways to us...