Feasibility of the assessment of cholesterol crystals in human macrophages using micro optical coherence tomography

• المؤلفون الرئيسيون: Tanaka, Atsushi, Kashiwagi, Manabu, Liu, Linbo, Chu, Kengyeh K., Sun, Chen-Hsin, Gardecki, Joseph A., Tearney, Guillermo J.
• مؤلفون آخرون: van Zandvoort, Marc
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/104865; http://hdl.handle.net/10220/20285

The presence of cholesterol crystals is a hallmark of atherosclerosis, but until recently, such crystals have been considered to be passive components of necrotic plaque cores. Recent studies have demonstrated that phagocytosis of cholesterol crystals by macrophages may actively precipitate plaque p...