Two combinatorial optimization problems for SNP discovery using base-specific cleavage and mass spectrometry

The discovery of single-nucleotide polymorphisms (SNPs) has important implications in a variety of genetic studies on human diseases and biological functions. One valuable approach proposed for SNP discovery is based on base-specific cleavage and mass spectrometry. However, it is still very challeng...

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Bibliographic Details
Main Authors: Chen, Xin, Wu, Qiong, Sun, Ruimin, Zhang, Louxin
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/105219
http://hdl.handle.net/10220/16762
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Institution: Nanyang Technological University
Language: English