Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure

Master transcription factors Oct4, Sox2, and Nanog are required to maintain the pluripotency and self-renewal of embryonic stem cells (ESCs) by regulating a specific transcriptional network. A few other transcription factors have been shown to be important in ESCs by interacting with these master tr...

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Bibliographic Details
Main Authors: Fang, Fang, Xu, Yifeng, Chew, Kai-Khen, Chen, Xi, Ng, Huck-Hui, Matsudaira, Paul
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/105306
http://hdl.handle.net/10220/20487
http://dx.doi.org/10.1002/stem.1705
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Institution: Nanyang Technological University
Language: English