Electrospun poly(L-Lactic Acid) nanofibres loaded with Dexamethasone to induce osteogenic differentiation of human mesenchymal stem cells

• Main Authors: Nguyen, Luong T. H., Liao, Susan, Chan, Casey K., Ramakrishna, Seeram
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2013
• 主題: DRNTU::Engineering::Materials
• 在線閱讀: https://hdl.handle.net/10356/105321; http://hdl.handle.net/10220/17685; http://www.tandfonline.com/doi/abs/10.1163/092050611X597807#.UnDNG3B0z5w
• 機構: Nanyang Technological University

Dexamethasone (Dex), a synthetic corticosteroid, was loaded into poly(L-lactic acid) (PLLA) nanofibrous scaffolds with a concentration of 0.333 wt% by electrospinning. The Dex-loaded PLLA nanofibres increased the mechanical strength in comparison with pure PLLA nanofibres. A sustained release prof...