Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells)
Fat-Inducing Transmembrane protein 2 (Fit2/Fitm2) is an evolutionarily conserved transmembrane protein. Located on the membrane of the endoplasmic reticulum(ER), Fit2 has been shown to play an important role [1] in the packaging of triglycerides into lipid droplets(LD) within adipocytes (Fig.1). Pan...
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2015
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sg-ntu-dr.10356-1055052020-09-27T20:28:08Z Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells) Koh, Tracy Yusuf Ali Lee Kong Chian School of Medicine (LKCMedicine) Fit2 Min6 cells Fat-Inducing Transmembrane protein 2 (Fit2/Fitm2) is an evolutionarily conserved transmembrane protein. Located on the membrane of the endoplasmic reticulum(ER), Fit2 has been shown to play an important role [1] in the packaging of triglycerides into lipid droplets(LD) within adipocytes (Fig.1). Pancreatic beta-cells (β-cells) secrete insulin. In diabetes β-cell dysfunction is driven partly by lipid stress (lipotoxicity). Fit2 is expressed in β-cells but its function remains elusive. [2nd Award] 2015-06-17T03:15:13Z 2019-12-06T21:52:41Z 2015-06-17T03:15:13Z 2019-12-06T21:52:41Z 2015 2015 Student Research Poster Koh, T. (2015, March). Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells). Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/105505 http://hdl.handle.net/10220/25934 en © 2015 The Author(s). application/pdf |
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Fit2 Min6 cells |
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Fit2 Min6 cells Koh, Tracy Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells) |
| description |
Fat-Inducing Transmembrane protein 2 (Fit2/Fitm2) is an evolutionarily conserved transmembrane protein. Located on the membrane of the endoplasmic reticulum(ER), Fit2 has been shown to play an important role [1] in the packaging of triglycerides into lipid droplets(LD) within adipocytes (Fig.1). Pancreatic beta-cells (β-cells) secrete insulin. In diabetes β-cell dysfunction is driven partly by lipid stress (lipotoxicity). Fit2 is expressed in β-cells but its function remains elusive. [2nd Award] |
| author2 |
Yusuf Ali |
| author_facet |
Yusuf Ali Koh, Tracy |
| format |
Student Research Poster |
| author |
Koh, Tracy |
| author_sort |
Koh, Tracy |
| title |
Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells) |
| title_short |
Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells) |
| title_full |
Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells) |
| title_fullStr |
Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells) |
| title_full_unstemmed |
Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells) |
| title_sort |
elucidating the role of fat-inducing transmembrane protein 2 (fit2) in insulin-producing beta-cells (β-cells) |
| publishDate |
2015 |
| url |
https://hdl.handle.net/10356/105505 http://hdl.handle.net/10220/25934 |
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1681056906822549504 |