Peptide inhibitors of viral assembly : a novel route to broad-spectrum antivirals

We investigated the potential of small peptide segments to function as broad-spectrum antiviral drug leads. We extracted the α-helical peptide segments that share common secondary-structure environments in the capsid protein–protein interfaces of three unrelated virus classes (PRD1-like, HK97-like,...

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Bibliographic Details
Main Authors: ElSawy, Karim M., Twarock, Reidun., Verma, Chandra S., Caves, Leo S. D.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/105681
http://hdl.handle.net/10220/17754
http://dx.doi.org/10.1021/ci200467s
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Institution: Nanyang Technological University
Language: English