Hidden sequence specificity in loading of single-stranded RNAs onto Drosophila Argonautes

Argonaute proteins play important roles in gene regulation with small RNAs (sRNAs) serving as guides to targets. Argonautes are believed to bind sRNAs in a sequence non-specific manner. However, we recently discovered that Argonautes selectively load endogenous single-stranded (ss) RNAs, suggesting...

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Bibliographic Details
Main Authors: Goh, Eling, Okamura, Katsutomo
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2019
Subjects:
RNA
Online Access:https://hdl.handle.net/10356/105742
http://hdl.handle.net/10220/48739
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Institution: Nanyang Technological University
Language: English