Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s disease

• Main Authors: Park, Jung Eun, Sze, Siu Kwan, Adav, Sunil Shankar
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2019
• 主題: Alzheimer’s Disease; Neurodegenerative Diseases; DRNTU::Science::Biological sciences
• 在線閱讀: https://hdl.handle.net/10356/105991; http://hdl.handle.net/10220/48813
• 機構: Nanyang Technological University

Mitochondrial dysfunction is a key feature in both aging and neurodegenerative diseases including Alzheimer’s disease (AD), but the molecular signature that distinguishes pathological changes in the AD from healthy aging in the brain mitochondria remain poorly understood. In order to unveil AD speci...