Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer’s disease with cerebrovascular disease

• Main Authors: Gallart-Palau, Xavier, Lee, Benjamin Sian Teck, Adav, Sunil Shankar, Qian, Jingru, Serra, Aida, Park, Jung Eun, Lai, Mitchell K. P., Chen, Christopher P., Kalaria, Raj N., Sze, Siu Kwan
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: DRNTU::Science::Biological sciences; Alzheimer’s Disease; Cerebrovascular Disease
• 在線閱讀: https://hdl.handle.net/10356/89979; http://hdl.handle.net/10220/46445
• 機構: Nanyang Technological University

Background: Dementia risk in women is higher than in men, but the molecular neuropathology of this gender difference remains poorly defined. In this study, we used unbiased, discovery-driven quantitative proteomics to assess the molecular basis of gender influences on risk of Alzheimer’s disease wit...