Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus

Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus

Background : Major alteration in lifestyle of human population has promoted Type 2 diabetes mellitus (T2DM) to the level of an epidemic. This metabolic disorder is characterized by insulin resistance and pancreaticβ-cell dysfunction and apoptosis, triggered by endoplasmic reticulum (ER) stress, oxid...

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Bibliographic Details
Main Authors: Dutta, Pritha, Ma, Lichun, Ali, Yusuf, Sloot, Peter M.A., Zheng, Jie
Other Authors: School of Computer Science and Engineering
Format: Article
Language:English
Published: 2019
Subjects:
Boolean Model
Type 2 Diabetes Mellitus
DRNTU::Science::Medicine
Online Access:https://hdl.handle.net/10356/105995
http://hdl.handle.net/10220/48812
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/105995
http://hdl.handle.net/10220/48812

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