Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus
Background : Major alteration in lifestyle of human population has promoted Type 2 diabetes mellitus (T2DM) to the level of an epidemic. This metabolic disorder is characterized by insulin resistance and pancreaticβ-cell dysfunction and apoptosis, triggered by endoplasmic reticulum (ER) stress, oxid...
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| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/105995 http://hdl.handle.net/10220/48812 |
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| Institution: | Nanyang Technological University |
| Language: | English |