High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in pseudomonas aeruginosa biofilms

High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in pseudomonas aeruginosa biofilms

Resistance to β-lactam antibiotics is a frequent problem in Pseudomonas aeruginosa lung infection of cystic fibrosis (CF) patients. This resistance is mainly due to the hyperproduction of chromosomally encoded β-lactamase and biofilm formation. The purpose of this study was to investigate the role o...

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Bibliographic Details
Main Authors: Wang, Hengzhuang, Ciofu, Oana, Yang, Liang, Wu, Hong, Song, Zhijun, Oliver, Antonio, Høiby, Niels
Other Authors: Singapore Centre for Environmental Life Sciences Engineering
Format: Article
Language:English
Published: 2015
Subjects:
DRNTU::Science::Biological sciences::Microbiology
Online Access:https://hdl.handle.net/10356/106011
http://hdl.handle.net/10220/26343
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/106011
http://hdl.handle.net/10220/26343

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