Extracellular DNA shields against aminoglycosides in pseudomonas aeruginosa biofilms

• المؤلفون الرئيسيون: Chiang, Wen-Chi, Nilsson, Martin, Jensen, Peter Østrup, Høiby, Niels, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim
• مؤلفون آخرون: Singapore Centre for Environmental Life Sciences Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Microbiology::Bacteria
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/103038; http://hdl.handle.net/10220/25803

Within recent years, it has been established that extracellular DNA is a key constituent of the matrix of microbial biofilms. In addition, it has recently been demonstrated that DNA binds positively charged antimicrobials such as aminoglycosides and antimicrobial peptides. In the present study, we p...