The cyclic AMP-Vfr signaling pathway in Pseudomonas aeruginosa is inhibited by cyclic di-GMP

• Main Authors: Almblad, Henrik, Harrison, Joe J., Rybtke, Morten, Groizeleau, Julie, Givskov, Michael, Parsek, Matthew R., Tolker-Nielsen, Tim
• Other Authors: Armitage, J. P.
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Bacteria
• Online Access: https://hdl.handle.net/10356/105675; http://hdl.handle.net/10220/26067
• Institution: Nanyang Technological University

The opportunistic human pathogen Pseudomonas aeruginosa expresses numerous acute virulence factors in the initial phase of infection, and during long-term colonization it undergoes adaptations that optimize survival in the human host. Adaptive changes that often occur during chronic infection give r...