Fluorescence-based reporter for gauging cyclic Di-GMP levels in Pseudomonas aeruginosa

• المؤلفون الرئيسيون: Borlee, Bradley R., Nielsen, Thomas E., Parsek, Matthew R., Rybtke, Morten Theil, Murakami, Keiji, Irie, Yasuhiko, Hentzer, Morten, Givskov, Michael, Tolker-Nielsen, Tim
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/100527; http://hdl.handle.net/10220/10971

The increased tolerance toward the host immune system and antibiotics displayed by biofilm-forming Pseudomonas aeruginosa and other bacteria in chronic infections such as cystic fibrosis bronchopneumonia is of major concern. Targeting of biofilm formation is believed to be a key aspect in the develo...