Induction of native c-di-GMP phosphodiesterases leads to dispersal of pseudomonas aeruginosa biofilms

• Main Authors: Andersen, Jens Bo, Kragh, Kasper Nørskov, Hultqvist, Louise Dahl, Rybtke, Morten, Nilsson, Martin, Jakobsen, Tim Holm, Givskov, Michael, Tolker-Nielsen, Tim
• 其他作者: Singapore Centre for Environmental Life Sciences and Engineering
• 格式: Article
• 語言: English
• 出版: 2021
• 主題: Engineering::Environmental engineering; Biofilm Dispersal; Phosphodiesterase
• 在線閱讀: https://hdl.handle.net/10356/153679
• 機構: Nanyang Technological University

A decade of research has shown that the molecule c-di-GMP functions as a central second messenger in many bacteria. A high level of c-di-GMP is associated with biofilm formation, whereas a low level of c-di-GMP is associated with a planktonic single-cell bacterial lifestyle. c-di-GMP is formed by di...