Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle

• Main Authors: Rai, Ragini, Zhu, Lei, Chen, Haifen, Gupta, Archana Patkar, Sze, Siu Kwan, Zheng, Jie, Ruedl, Christiane, Bozdech, Zbynek, Featherstone, Mark
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/106127; http://hdl.handle.net/10220/24984
• Institution: Nanyang Technological University

Background: Over the course of its intraerythrocytic developmental cycle (IDC), the malaria parasite Plasmodium falciparum tightly orchestrates the rise and fall of transcript levels for hundreds of genes. Considerable debate has focused on the relative importance of transcriptional versus post-tr...